So far, most of us have heard of cannabidiol (also known as CBD). However, besides the well-known and established CBD, there also exists CBG (short for cannabigerol). A non-psychoactive cannabinoid deriving from the cannabis plant. Most cannabis seeds contain only about 1% of CBG, but its qualities are gaining more and more attention from health professionals and consumers. Besides CBD oil, there’s also CBG oil, too.

Let’s get more into detail about CBG

It is important to understand some basic terms before discussing CBG and the differences between CBD and CBG. First of all, the term “cannabinoid” refers to substances that interact with the cannabinoid receptors in the human body. CB1 and CB2 are the two most important cannabinoid receptors in the body. To be more precise CB1 is being associated with the human nervous system, whereas CB2 is related when speaking about inflammation. Cannabinoids and their receptors are part of the human body system and can help according to scientists against pain or inflammation.

This connection between cannabinoids and the human body system is called the endocannabinoid system (ECS). Our body produces its own cannabinoids, so-called endocannabinoids. From which the commonly called anandamide and 2-arachidonoylglycerol (2-AG are the two most substantial ones. The cannabis plant contains hundreds of substances that have similar biological functions, including many plant-based cannabinoids (phytocannabinoids).

But what about CBG oil?

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The two phytocannabinoids best known to people are cannabidiol (CBD) and tetrahydrocannabinol (THC). Basically, CBD and THC affect the human body by interacting with our CB1 and CB2 receptors. Besides CBD and THC, there exist several other phytocannabinoids derived from a parent cannabinoid called cannabigerol acid (CBGA). CBGA is the pre-stage type to the acidic forms of THC and CBD called THCA and CBDA. After being processed with heat, THCA and CBDA transform into THC and CBD. CBD is the acidic form of CBDA and CBG is the non-acidic version of CBGA. Both types, as well as neutral cannabinoids, can have effects on the human body.

Differences between THC, CBD, and CBG

The main difference between CBD and THC is that THC can make you feel high, whereas CBD does not have psychoactive effects. Most of the research on CBD has focused on the prevention of seizures and the Food and Drug Administration (FDA) has recently approved CBD as a pharmaceutical treatment therapy for use in children suffering from severe seizures. Additional research shows, that CBD may be a potentially beneficial therapy against anxiety and inflammation, and may even have cancer-inhibiting qualities.

There’s also a difference between CBD oil and CBG oil.

Although CBG is similar to the more well-known CBD when it comes to its non-psychoactive effects, there have been conducted far less research regarding the impact of CBG on the human body. Nevertheless, the interest in CBG is rising as it’s assumed that both cannabinoids (CBD and CBG) may have different positive effects on the human body.

Potential Benefits of CBG

Studies on animals have shown that CBG stimulates the receptors responsible for the perception of pain and heat. It furthermore can stimulate receptors in the brain and blood vessels responsible for blood pressure regulation. Therefore, CBG could potentially contribute to high blood pressure and could also help against inflammation in the body.
All of these effects have also been observed with CBD. Thus, it’s still not certain whether CBG, which again is produced in much lower quantities by the cannabis plant, has any different effects.
Moreover, two studies on animals have shown that CBG may be beneficial in inflammatory bowel disease (like Ulcerative colitis and Crohn’s disease) and Huntington’s disease (an incurable brain disease). Further clinical studies have also revealed that CBG may have anti-bacterial effects and may be beneficial against colorectal cancer prevention.

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CBG, together with some other cannabinoids, has shown antibacterial effects. When researchers tested it against various strains of the bacterium “Staphylococcus aureus” in a laboratory, CBG was found to have significant antimicrobial effects. This finding could be of particular importance, as antibiotic resistance is becoming more common and important nowadays.
In addition, CBG may increase dopamine levels as well as support a more relaxing sleep and stimulate appetite regulation. Although there is some evidence indicating promising benefits of CBG, it is obvious that more research and clinical trials need to be conducted before final conclusions can be drawn.